Clinical uses of 2,3-dimercaptopropanol (BAL); the effect of BAL on the excretion of arsenic in arsenical intoxication.

نویسندگان

  • J A LUETSCHER
  • H EAGLE
  • W T LONG-COPE
چکیده

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منابع مشابه

Clinical Uses of 2,3-dimercaptopropanol (bal). Vii. the Treatment of Arsenical Dermatitis with Preparations of Bal.

The development of 2,3-dimercaptopropanol (British Anti-Lewisite, BAL) by Peters, Stocken, and Thompson (1) has made available a potent antidote for arsenical poisoning. Study of the chemical combination of arsenic with sensitive enzymes and cells indicated that the arsenic could, under certain circumstances, be removed from the cells, and that enzymes could be reactivated by the action of BAL ...

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Clinical Uses of 2,3-dimercaptopropanol (bal). X. the Treatment of Acute Systemic Mercury Poisoning in Experimental Animals with Bal, Thiosorbitol and Bal Glucoside.

Although chemical agents were not employed as offensive weapons during the past war, nevertheless it was imperative to pursue vigorously investigations on the treatment of chemical warfare casualties. Inasmuch as a number of chemical warfare agents contain arsenic, attention was focused on the synthesis of compounds capable of antagonizing the local and systemic effects of arsenical vesicants. ...

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Clinical Uses of 2,3-dimercaptopropanol (bal). X. the Treatment of Acute Systemic Mercury Poisoning

Although chemical agents were not employed as offensive weapons during the past war, nevertheless it was imperative to pursue vigorously investigations on the treatment of chemical warfare casualties. Inasmuch as a number of chemical warfare agents contain arsenic, attention was focused on the synthesis of compounds capable of antagonizing the local and systemic effects of arsenical vesicants. ...

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Use of BAL in the Treatment of Arsenical Neuropathy

BAL 01* British Anti-Lewisite which is 2, 3 dimercaptopropanol was evolved in Professor Peters' Laboratory at Oxford by Peters, Stocken and Thompson in 1945, as an effective antidote to Lewisite. It has since been used successfully in several forms of metallic poisoning including arsenic, mercury and other heavy metals. Eagle and Magnuson (1946) found it efficacious in 5 cases of arsenical ence...

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عنوان ژورنال:
  • The Journal of clinical investigation

دوره 25 4  شماره 

صفحات  -

تاریخ انتشار 1946